Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/791
Title: To Decipher the Role of Neuropeptides to Regulate Reversal Frequency in the Global Search Behaviour of C. elegans
Authors: Lal, Mohan
Keywords: Biology
C.elegans
Neuropeptides
Protein
Issue Date: 13-Jul-2017
Publisher: IISER-M
Abstract: In C. elegans, during exploratory behavior the switch from local to global search for food is an important for survival and being mediated by the neuropeptides. Previous studies have shown that the FLP-18 neuropeptide is regulating the reversal frequency in global search behavior through NPR-4, one of its G protein coupled receptor . Here we are looking for receptors of FLP-18 and other probable neuropeptides that play role in neuromodulation of exploratory behavior. In our studies, we found FLP-1 and FLP-21 neuropeptides along with FLP-18 regulates reversal frequency during both local and global search of exploratory behavior. Furthermore, FLP-18 also functions through NPR-1 receptor along with NPR-4 receptor. The implication of these studies is that information ow through C. elegans circuits depends on neuromodulatory states.
URI: http://hdl.handle.net/123456789/791
Appears in Collections:MS-12

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