Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/588
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dc.contributor.authorM, Aiswarya Joy-
dc.date.accessioned2016-09-06T12:52:31Z-
dc.date.available2016-09-06T12:52:31Z-
dc.date.issued2016-08-09-
dc.identifier.urihttp://hdl.handle.net/123456789/588-
dc.description.abstractC. elegans can sense a variety of volatile as well as gustatory cues through its highly developed chemosensory system. In this project, the role of a cation selective excitatory GABA receptor in chemotactic response to various volatile chemicals was investigated. Interestingly it was found that loss of function mutants of exp-1 avoided isoamyl alcohol, an attractant for wild-type worms. When the response to other volatile attractants was investigated it was noticed that the particular set of attractants sensed through AWC amphid sensory neuron was being avoided. Upon performing pan-neuronal (using promoter for rab-3) rescue for exp-1 mutants phenotypes, it was to found that exp-1 mutant related phenotypes were partially rescued which confirmed that altered chemotactic response of exp-1 mutant was a neuronal defect. Further other behaviours those are triggered by AWC neuron – reversals and omega turns (Ω) were observed. They were also found to be defective confirming the essential role of EXP-1 in AWC neuron-dependent phenotypes.en_US
dc.description.sponsorshipIISER-Men_US
dc.language.isoenen_US
dc.publisherIISER-Men_US
dc.subjectBiologyen_US
dc.subjectC.elegansen_US
dc.subjectChemosensory Systemen_US
dc.titleInvestigating the Role of EXP-1, a Cation Selective Excitatory GABA Receptor in Chemotaxis Towards Volatile Attractantsen_US
dc.typeThesisen_US
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