Elucidating the Role of Gpr114 in Immunological Memory: Attempts at Ligand Identification

Abstract

First attempts were made in identifying the ligand, however the future studies will focus on confirming weather one or more of these are putative ligand/s, Cloning and expression of that putative ligand,Co-IP Experiments, by using the Ligand. Then will decipher the downstream signaling events in CD8+T cells mediated by the interaction of gpr114 and its receptor