Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/493
Full metadata record
DC FieldValueLanguage
dc.contributor.authorL.V, Shiji-
dc.contributor.otherBabu, Kavita-
dc.date.accessioned2015-07-10T11:24:10Z-
dc.date.available2015-07-10T11:24:10Z-
dc.date.issued2015-07-10-
dc.identifier.urihttp://hdl.handle.net/123456789/493-
dc.descriptionMS10045en_US
dc.description.abstractMultidrug resistance associated proteins (mrps) belong to the C subfamily of ABC transporters. There are 9 mrps in C.elegans. Most of them are anion transporters. In this project we studied the role of MRPs in neuronal signaling; more precisely in dopaminergic signaling. We utilized SWIP (Swimming induced paralysis) assay to characterize mrps for their role in dopaminergic signaling. Next rescue was performed with exogenous dopamine (DA).In this study we identified mrp-3 as a probable mrp candidate that could play a role in dopaminergic signaling. Further studies will be done by utilizing various dopaminergic pathway mutants to identify the role of mrp-3 in the pathway.en_US
dc.description.sponsorshipIISER Men_US
dc.language.isoenen_US
dc.publisherIISER Men_US
dc.subjectProteinsen_US
dc.subjectBiologyen_US
dc.subjectNervous Systemen_US
dc.titleInvestigating the role of Multidrug Resistance associated proteins in Caenorhabditis elegans nervous systemen_US
dc.typeThesisen_US
Appears in Collections:MS-10

Files in This Item:
File Description SizeFormat 
MS10045.pdf23.16 kBAdobe PDFView/Open


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.