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Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1671
Title: Binding of pyrimidine tract with RRM motif using U2AF65
Authors: Kumar, Shivam.
Sharma, Monika
Keywords: Binding
Pyrimidine
U2AF65
Issue Date: 28-Jul-2021
Publisher: IISERM
Abstract: To study the molecular mechanisms of the recognition of the 3 -splice-site-assosciated polypyrimidine tract RNA by the large subunit of the human U2 snRNP auxiliary factor U2AF65 as a key early step in pre-mRNA splicing. The tandem RNA recognition motif domains of U2AF65 adopt two remarkably dis- tinct domain arrangements in the absence or presence of a strong (that is, high affinity) polypyrimidine tract.
URI: http://hdl.handle.net/123456789/1671
Appears in Collections:MS-16

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