Please use this identifier to cite or link to this item:
http://hdl.handle.net/123456789/1129
Title: | Comparative structural studies of peptide transporters and their roles in physiological processes |
Authors: | Bhojane, Shubham |
Keywords: | Mammalian Homologues Drug Promiscuity Transmembrane α-helical Spanner |
Issue Date: | 20-Nov-2019 |
Publisher: | IISERM |
Abstract: | The POT family of membrane transporter proteins shows remarkable feature of diverse substrate promiscuity. This promiscuity has led to development of peptide based pro-drugs that us PepT1 and PepT2, mammalian homologues, to improve oral drug delivery. Here I tried to classify 46 POT family transporters on the basis of transmembrane α-helical spanners and to establish evolutionary relationship between POT family members and by sequence alignment technique looked into residues conserved in POT family members. |
URI: | http://hdl.handle.net/123456789/1129 |
Appears in Collections: | MS-14 |
Files in This Item:
File | Description | Size | Format | |
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MS14020.pdf | 101.01 kB | Adobe PDF | View/Open |
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