Please use this identifier to cite or link to this item: http://hdl.handle.net/123456789/1129
Title: Comparative structural studies of peptide transporters and their roles in physiological processes
Authors: Bhojane, Shubham
Keywords: Mammalian Homologues
Drug
Promiscuity
Transmembrane α-helical Spanner
Issue Date: 20-Nov-2019
Publisher: IISERM
Abstract: The POT family of membrane transporter proteins shows remarkable feature of diverse substrate promiscuity. This promiscuity has led to development of peptide based pro-drugs that us PepT1 and PepT2, mammalian homologues, to improve oral drug delivery. Here I tried to classify 46 POT family transporters on the basis of transmembrane α-helical spanners and to establish evolutionary relationship between POT family members and by sequence alignment technique looked into residues conserved in POT family members.
URI: http://hdl.handle.net/123456789/1129
Appears in Collections:MS-14

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