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Showing results 691 to 710 of 1776 < previous   next >
Issue DateTitleAuthor(s)
14-Jul-2017Ice Ice Baby Evolution of Cold Shock Resistance Mechanisms in Drosophila melanogasterSingh, Akanksha
Apr-2022Identification & Characterization of conserved microRNAs in Drosophila immune responsesThe microRNAs are small non coding RNAs of length ~ 20-22 base pair and are involved in post- transcriptional regulation of gene regulation. They associate with a protein known as Argonaute to form RNA-induced silencing complex (RISC) which repress or degrade mRNAs in a sequence dependent manner. Many miRNAs are known to play key role in many important cellular processes such as metabolism, differentiation, immune system etc. Their role in both innate and adaptive immune responses is very well studied in the past decade. However, not much is known about their role in insect innate responses. Drosophila melanogaster and Bombyx mori provide a good model to study innate immune responses. Being part of closely related order, they can also be used to determine conservation in the role of miRNA in innate immune responses. The current work unravels 79 miRNAs are conserved between the two species with sequence identity of >95%. Major immune response in Drosophila includes hemolymph and fat body. The current work demonstrates that 30 miRNAs out of the 79 are found to be expressing in the hemolymph of Drosophila under normal conditions. Expression of five miRNAs is also validated in Drosophila larval fat body. Infecting Drosophila larvae with gram-negative bacteria like E. coli induces Imd signaling pathway in which the antimicrobial peptide (AMP), Diptericin (Dpt) is up- regulated. The level of up-regulation depends on the time for which the larvae are incubated. Initial expression analysis shows that the levels of miR-184-5p are downregulated during E. coli infection. But several technical issues need to be addressed before this can be established.; Bhatt, Saurabh
May-2020Identification and characterization of Rabip4' interaction partnersGitanjali; Sharma, Mahak
Apr-2022Identification and Characterization of Unknwn Iron Deficiency Responsive Genes in Arabidopsis thalianaJaryal, Shivangini
May-2020Identification and heterologous expression of labdane-type type diterpene synthases from Sesamum indicum in Saccharomyces cerevisiaeAshim, Ananya; Bachhawat, A.K.
8-Jul-2015Identification of SNAREs that interact with mammalian HOPS complex to mediate late endosome-lysosome fusion.Saleem, Irfana; Sharma, Mahak
13-Jul-2017Identification of Sulphur Dioxide Sources Using in-situ Measurements at a Sub-urban Site in the North-West Indo-Gangetic PlainS.S, Nimya
Apr-2022Identification of venom-neutralizing nanobodies and developing a rapid nanobody selection platformDubey, Abhishek
29-Jul-2015Identifying genes to increase flux in the isoprenoid pathway in S. cerevisiaeLourembam, Thoithoi; Bachhawat, Anand Kumar
13-Jul-2017Identifying New Players Involved in Ubiquinone Biosynthesis in Escherichia coliBalecha, Himanshi
Apr-2022Identifying the specificity determinants for DUB processivity in sde2-ubl in vivoSajeevan, Aiswarya
Jun-2020iLens Interferometer Probing Micro-scale SystemsTyagi, Ayush; Singh, K.P.
May-2020Imaging electric and magnetic orders using scanning probe microscopySajan, Sheet, G. Sandra
May-2020Imaging of blood vessels in finger joints using dual wavelength lasers and transmission techniquesAsif, Mohammed L.; Biswas, S.K .
26-Jun-2015Imaging, Domain Writing and Spectroscopy using Scanning ProbesArora, Ashima
13-Aug-2015Immunological Studies on the Role of GPR114 and Russell’s Viper VenomDadwal, Nirdosh
15-Jul-2017Immunomodulatory Studies During Viral InfectionsMathew, Amal
May-2023Impact of entomopathogenic fungus Metarhizium on different wolbachia infected Nasonia vitripennisSaini, Sargam
2-Nov-2018Impact of Open Fires on Atmospheric Chemistry over the North-West Indo- Gangetic Plain Quantified Using Multi-Year OH Reactivity and Trace Gas MeasurementsKumar, Vinod
May-2023Impact of varying adult sex ration on temporary female ornamentation in pomatoschistus minutusMahajan, Ayushi
Showing results 691 to 710 of 1776 < previous   next >